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pentobarbital will lessen the extent or impact of artemether/lumefantrine by affecting hepatic/intestinal enzyme CYP3A4 metabolism. Keep away from or Use Alternate Drug. Coadministration with robust CYP3A4 inducers may end up in lowered serum concentrations and loss of antimalarial efficacyPhenobarbital lowers the plasma levels of dicumarol (identi